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Phenotypes Associated with This Genotype
Genotype
MGI:5544094
Allelic
Composition		 Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+
Tg(KRT5-cre)5132Jlj/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igs1tm11(CAG-Bgeo,-Edn2)Nat mutation (1 available); any Igs1 mutation (10 available)
Tg(KRT5-cre)5132Jlj mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Absence of vascular defects in the skin of adult Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+ Tg(KRT5-cre)5132Jlj/0 mice

integument
abnormal dermal pigmentation ( J:201133 )
• massive increase in dermal pigmentation

pigmentation
abnormal dermal pigmentation ( J:201133 )
• massive increase in dermal pigmentation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory