About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5544090
Allelic
Composition		 Ednrbtm1.1Nat/Ednrbtm1.2Nat
Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+
Tg(Pax6-cre,GFP)2Pgr/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrbtm1.1Nat mutation (1 available); any Ednrb mutation (105 available)
Ednrbtm1.2Nat mutation (0 available); any Ednrb mutation (105 available)
Igs1tm11(CAG-Bgeo,-Edn2)Nat mutation (1 available); any Igs1 mutation (10 available)
Tg(Pax6-cre,GFP)2Pgr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal retina vasculature morphology ( J:201133 )
• removal of Ednrb appears to sensitize the vasculature as growth arrests proximal to the front of cre-mediated recombination

cardiovascular system
abnormal retina vasculature morphology ( J:201133 )
• removal of Ednrb appears to sensitize the vasculature as growth arrests proximal to the front of cre-mediated recombination

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory