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Phenotypes Associated with This Genotype
Genotype
MGI:5544087
Allelic
Composition
Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+
Tg(Pdgfra-cre)1Clc/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igs1tm11(CAG-Bgeo,-Edn2)Nat mutation (1 available); any Igs1 mutation (10 available)
Tg(Pdgfra-cre)1Clc mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Interstitial tip cells in adult Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+ Tg(Pdgfra-cre)1Clc/0 retinas

vision/eye
• intraretinal capillaries are larger and more numerous; however a large number of these terminate with blind endings
• blind endings are most numerous in the inner plexiform layer and are typically decorated with multiple filopodia

cardiovascular system
• intraretinal capillaries are larger and more numerous; however a large number of these terminate with blind endings
• blind endings are most numerous in the inner plexiform layer and are typically decorated with multiple filopodia


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory