Phenotypes Associated with This Genotype

Genotype
MGI:5543911

• Allelic Composition: Tg(Amh-SMAD2*)#Jebu/0; Trp53^tm1Brn/Trp53^tm1Brn
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

increased ovarian teratoma incidence ( J:200783 )

♀ • 2 of 6 mice injected with an adenovirus expressing cre recombinase into the bursa develop teratoma 3 months after injection

ovary cyst ( J:200783 )

♀ • 1 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop fluid-filled bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 or 6 months after injection

reproductive system

increased ovarian teratoma incidence ( J:200783 )

♀ • 2 of 6 mice injected with an adenovirus expressing cre recombinase into the bursa develop teratoma 3 months after injection

ovary cyst ( J:200783 )

♀ • 1 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop fluid-filled bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 or 6 months after injection

neoplasm

increased ovarian teratoma incidence ( J:200783 )

♀ • 2 of 6 mice injected with an adenovirus expressing cre recombinase into the bursa develop teratoma 3 months after injection

growth/size/body

ovary cyst ( J:200783 )

♀ • 1 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop fluid-filled bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 or 6 months after injection