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Phenotypes Associated with This Genotype
Genotype
MGI:5543893
Allelic
Composition		 Elavl1tm1Lix/Elavl1tm1Lix
Tg(Scgb1a1-rtTA)2Jaw/0
Tg(tetO-cre)1Jaw/0
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elavl1tm1Lix mutation (0 available); any Elavl1 mutation (42 available)
Tg(Scgb1a1-rtTA)2Jaw mutation (1 available)
Tg(tetO-cre)1Jaw mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased inflammatory response ( J:204952 )
• reduced pulmonary inflammation in mice treated with doxycycline and intranasal rIL17
lung inflammation ( J:204952 )
• reduced pulmonary inflammation in mice treated with doxycycline and intranasal rIL17

respiratory system
lung inflammation ( J:204952 )
• reduced pulmonary inflammation in mice treated with doxycycline and intranasal rIL17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory