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Phenotypes Associated with This Genotype
Genotype
MGI:5538522
Allelic
Composition		 Fgfr3tm1Dor/Fgfr3tm1Dor
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-Fgf9,-EGFP)#Dor/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr3tm1Dor mutation (1 available); any Fgfr3 mutation (52 available)
Tg(SFTPC-rtTA)5Jaw mutation (5 available)
Tg(tetO-Fgf9,-EGFP)#Dor mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased organ/body region tumor incidence ( J:204282 )
• at 1 week or 1 month of induction with doxycycline, mutants do not exhibit formation of lung tumors and lung histology remains normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory