Analysis Tools
respiratory system
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• doxycycline treated embryos exhibit an extended domain of blood vessels into the expanded lung mesenchyme at E13.5
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• beginning at E12.5, doxycycline treated embryos exhibit enlarged lung size
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• doxycycline treated embryos exhibit increased luminal space, fewer epithelial airways and a wide band of mesenchyme separating epithelial ducts at E14.5
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• doxycycline treated embryos exhibit a reduction in epithelial branching at E11.5 and E12.5
• beginning at E12.5, doxycycline treated embryos exhibit an arrest in branching and luminal dilation
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• doxycycline treated embryos exhibit a large mesenchymal expansion in the lungs at E11.5 and E12.5
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• doxycycline treated embryos show an absence of smooth muscle in the sub-epithelial compartment of lungs at E14.5, although it is present surrounding large blood vessels
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cardiovascular system
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• doxycycline treated embryos exhibit an extended domain of blood vessels into the expanded lung mesenchyme at E13.5
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growth/size/body
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• beginning at E12.5, doxycycline treated embryos exhibit enlarged lung size
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