Phenotypes for Hba Hbb MGI:5529820 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hba^tm1Paz/Hba⁺ Hbb^tm1Tow/Hbb^tm1Tow
Genetic Background	involves: 129S2/SvPas * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hba^tm1Paz mutation (2 available); any Hba mutation (11 available)
Hbb^tm1Tow mutation (1 available); any Hbb mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal erythroid progenitor cell morphology ( J:204029 )

• a small population of Ter119+ CD71^low fetal liver cells unlike in wild-type mice

decreased erythroid progenitor cell number ( J:204029 )

• greater impairment of Ter119+ CD71^hi cells than in double homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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