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Phenotypes Associated with This Genotype
Genotype
MGI:5529820
Allelic
Composition		 Hbatm1Paz/Hba+
Hbbtm1Tow/Hbbtm1Tow
Genetic
Background		 involves: 129S2/SvPas * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hbatm1Paz mutation (2 available); any Hba mutation (10 available)
Hbbtm1Tow mutation (1 available); any Hbb mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythroid progenitor cell morphology ( J:204029 )
• a small population of Ter119+ CD71low fetal liver cells unlike in wild-type mice
decreased erythroid progenitor cell number ( J:204029 )
• greater impairment of Ter119+ CD71hi cells than in double homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory