About   Help   FAQ
Phenotypes Associated with This Genotype
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
• increase is seen during the night time
• increase is seen during the night time
• 2-fold increase in nocturnal stereotypic activities, including grooming, head bopping, and licking
• however, daytime activity levels are normal
• the increase in stereotypic activity and total horizontal distance traveled that is seen in wild-type mice due to administration of methylphenidate, a dopamine reuptake blocker, is attenuated by about 40% and 50% in mutants, respectively

• mutants weight approximately 10-20% less than controls up to 21 weeks of age
• males show a greater reduction in weight than females, weighing about 22% less than control males at 21-27 weeks of age
• females weigh approximately 9.5% less than control females at 21-27 weeks of age

• elevation in total T4 and free T4 level
• however, no differences in total T3 levels and serum TSH is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.07
The Jackson Laboratory