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Phenotypes Associated with This Genotype
Genotype
MGI:5527554
Allelic
Composition		 Flot2tm1Mak/Flot2tm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flot2tm1Mak mutation (1 available); any Flot2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell morphology ( J:203238 )
• mouse embryonic fibroblasts fail to form functional flotilin
• however, caveolar membrane microdomains form

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory