Phenotypes Associated with This Genotype

Genotype
MGI:5527266

• Allelic Composition: Del(15Krt7-Krt18)1Tmm/+; Tg(ACTB-KRAS*G12V,-luc)#Lche/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lung tumor incidence ( J:199528 )

• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors within 6 weeks of AdCre treatment

• tumor load and size of AdCre treated mice is similar to that seen in single Tg(Actb-KRAS*G12V,-luc)#Lche mice

respiratory system

increased lung tumor incidence ( J:199528 )

• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors within 6 weeks of AdCre treatment

• tumor load and size of AdCre treated mice is similar to that seen in single Tg(Actb-KRAS*G12V,-luc)#Lche mice