Phenotypes Associated with This Genotype

Genotype
MGI:5527168

• Allelic Composition: Syde1^{tm1a(EUCOMM)Hmgu}/Syde1^{tm1a(EUCOMM)Hmgu}
• Genetic Background: involves: C57BL/6N
• Cell Lines: HEPD0665_7_C10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:201692 )

N • mice exhibit normal cerebellum and hippocampus gross morphology and paired-pulse ratio

abnormal synaptic vesicle number ( J:201692 )

• reduced docked vesicles in CA1 synapses

abnormal miniature excitatory postsynaptic currents ( J:201692 )

• reduced frequency

• however, miniature excitatory postsynaptic current amplitudes are normal

cellular

abnormal synaptic vesicle number ( J:201692 )

• reduced docked vesicles in CA1 synapses