Phenotypes Associated with This Genotype

Genotype
MGI:5526949

• Allelic Composition: Usp14^ax-J/Usp14^ax-J
• Genetic Background: C.Cg-Usp14^ax-J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:203043 )

ataxia ( J:203043 )

mortality/aging

premature death ( J:203043 )

• Background Sensitivity: mice on a congenic BALB/c background die prematurely after developing adult-onset neuromuscular degeneration, similar to that of nmf375 homoyzygotes on the BALB/c background, but do live to at least 7 month of age unlike homozygotes on a C57BL/6J background which die at or before birth.

muscle

progressive muscle weakness ( J:203043 )