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Phenotypes Associated with This Genotype
Genotype
MGI:5526091
Allelic
Composition
Tg(Actb-KRAS*G12V,-luc)#Lche/0
Genetic
Background
involves: C57BL/6 * FVB/N
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No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors after 6-8 weeks
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

neoplasm
• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors after 6-8 weeks
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
lung cancer DOID:1324 OMIM:211980
OMIM:608935
OMIM:612571
OMIM:612593
OMIM:614210
J:199528


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory