Mouse Genome Informatics
tg
    Tg(Actb-KRAS*G12V,-luc)#Lche/0
involves: C57BL/6 * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors after 6-8 weeks
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas
• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:199528