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Phenotypes Associated with This Genotype
Genotype
MGI:5524990
Allelic
Composition		 Bcrtm1(BCR/ABL)Tsr/Bcr+
Genetic
Background		 C57BL/6-Bcrtm1(BCR/ABL)Tsr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcrtm1(BCR/ABL)Tsr mutation (1 available); any Bcr mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased hematopoietic stem cell number ( J:203111 )
• number of hematopoietic stem cells is decreased in young (1-3 month old) mice
abnormal bone marrow cell physiology ( J:203111 )
• bone marrow cells from mutant mice exhibit a competitive disadvantage when cotransplanted into lethally irradiated mice with wild type bone marrow cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory