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Phenotypes Associated with This Genotype
Genotype
MGI:5524279
Allelic
Composition		 Gt(ROSA)26Sortm1(TMPRSS2/ERG)Key/Gt(ROSA)26Sortm1(TMPRSS2/ERG)Key
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129 * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(TMPRSS2/ERG)Key mutation (2 available); any Gt(ROSA)26Sor mutation (1095 available)
Tg(Pbsn-cre)4Prb mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
prostate gland ventral lobe hyperplasia ( J:200002 )
• focal ventral lobe hyperplasia after 1 year of age in 50% of mice

endocrine/exocrine glands
prostate gland ventral lobe hyperplasia ( J:200002 )
• focal ventral lobe hyperplasia after 1 year of age in 50% of mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory