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Phenotypes Associated with This Genotype
Genotype
MGI:5523888
Allelic
Composition
Scn1atm2.1Kzy/Scn1a+
Tg(Pvalb-cre)1Tama/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn1atm2.1Kzy mutation (1 available); any Scn1a mutation (114 available)
Tg(Pvalb-cre)1Tama mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• some mice develop recurrent seizures after P16

mortality/aging
• some mice develop recurrent seizures after P16 and experience sporadic sudden death

nervous system
• some mice develop recurrent seizures after P16

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Dravet syndrome DOID:0080422 OMIM:607208
J:202863


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory