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Phenotypes Associated with This Genotype
Genotype
MGI:5523778
Allelic
Composition
Flt1tm1.1Fong/Flt1tm1.1Fong
Kdrtm1Jrt/Kdr+
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic
Background
involves: 129 * C57BL/6NCr * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt1tm1.1Fong mutation (1 available); any Flt1 mutation (76 available)
Gt(ROSA)26Sortm1(cre/ERT2)Thl mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
Kdrtm1Jrt mutation (1 available); any Kdr mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• in the brain and liver of tamoxifen treated mice compared with control mice but not as severe as in mice also lacking the Kdr null allele
• some small focal areas in the retina in tamoxifen-treated mice relative to mice lacking the Kdr null allele
• however, angiogenesis in the heart is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory