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Phenotypes Associated with This Genotype
Genotype
MGI:5523683
Allelic
Composition		 Notch2tm3.1Rko/Notch2tm3.1Rko
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch2tm3.1Rko mutation (0 available); any Notch2 mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:198632 )
N
• kidneys have functional nephrons in normal numbers; the absence of the Notch2 intracellular domain (N2ICD) does not affect nephron formation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory