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Phenotypes Associated with This Genotype
Genotype
MGI:5523444
Allelic
Composition		 Cd44tm1.1Ugu/Cd44tm1.1Ugu
Genetic
Background		 SJL.129(Cg)-Cd44tm1.1Ugu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44tm1.1Ugu mutation (9 available); any Cd44 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with PLP139-151
decreased susceptibility to experimental autoimmune encephalomyelitis ( J:199279 )
• delayed onset with reduced symptoms, fewer inflammatory infiltrates and increased apoptotic activity

hematopoietic system
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with PLP139-151

cellular
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with PLP139-151

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory