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Phenotypes Associated with This Genotype
Genotype
MGI:5522980
Allelic
Composition
Hoxatm1.1Ssp/Hoxatm1.1Ssp
Hoxdtm1.1Ssp/Hoxd+
Genetic
Background
involves: 129 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• anteriorization of the uterus is exacerbated compared to mice homozygous for the Hoxa mutation alone
• coiled for nearly half the length
• uteri closely resemble oviducts
• reduction of the stromal layer and an increase in luminal branching
• extremely thin
• smaller tubules which resemble those in the more anterior caput
• smaller with an extremely thin muscle layer, thinning is more severe than in mice homozygous for the Hoxa mutation alone
• smaller caudal epididymis
• significant enhancement of the anteriorization compared to mice homozygous for the Hoxa mutation alone
• extreme coiling from the epididymal junction extending posterior for approximately one-third of the length
• resembles the wild-type caudal epididymis with thinner muscle and stromal layers


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory