Phenotypes Associated with This Genotype

Genotype
MGI:5522979

• Allelic Composition: Hoxa^tm1.1Ssp/Hoxa⁺; Hoxd^tm1.1Ssp/Hoxd^tm1.1Ssp
• Genetic Background: involves: 129 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal testis morphology ( J:198638 )

♂ • canalicular testes located just above the scrotum are more commonly seen

unilateral cryptorchism ( J:198638 )

♂ • unilateral cryptorchidism is rarely seen

abnormal uterus morphology ( J:198638 )

♀ • slight coiling at the anterior end

♀ • reduction of the stromal layer and an increase in luminal branching

thin myometrium ( J:198638 )

♀

thin uterus ( J:198638 )

♀

abnormal cauda epididymis morphology ( J:198638 )

♂ • smaller with a thinner muscle layer

♂ • resembles the more anterior caput segment

small epididymis ( J:198638 )

♂ • smaller caudal epididymis

abnormal vas deferens morphology ( J:198638 )

♂ • typically display coiling of the proximal end

♂ • reduced muscle layer, particularly in the anterior portion

female infertility ( J:198638 )

♀

endocrine/exocrine glands

abnormal testis morphology ( J:198638 )

♂ • canalicular testes located just above the scrotum are more commonly seen

unilateral cryptorchism ( J:198638 )

♂ • unilateral cryptorchidism is rarely seen