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Phenotypes Associated with This Genotype
Genotype
MGI:5521398
Allelic
Composition		 Egln1tm1.1Fsl/Egln1+
Genetic
Background		 C57BL/6-Egln1tm1.1Fsl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egln1tm1.1Fsl mutation (1 available); any Egln1 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased spleen weight ( J:202737 )
• spleen weight is increased as compared to wild-type
polycythemia ( J:202737 )
• mice exhibit erythrocytosis, however, erythropoietin levels are not increased

immune system
increased spleen weight ( J:202737 )
• spleen weight is increased as compared to wild-type

respiratory system
increased tidal volume ( J:202737 )
• under normoxia conditions
increased pulmonary ventilation ( J:202737 )
• under normoxia conditions

growth/size/body
increased spleen weight ( J:202737 )
• spleen weight is increased as compared to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory