About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5521200
Allelic
Composition		 Ndufaf2tm1.1Itl/Ndufaf2tm1.1Itl
Genetic
Background		 involves: 129S/SvEv * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndufaf2tm1.1Itl mutation (1 available); any Ndufaf2 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitochondrial ATP synthesis coupled electron transport ( J:201547 )
• skin fibroblasts exhibit decreased complex 1 activity in the mitochondria compared with wild-type cells
• however, skin fibroblasts exhibit complex 1 assembly in the mitochondria

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory