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Phenotypes Associated with This Genotype
Genotype
MGI:5517583
Allelic
Composition		 Ptgdr2tm1Tasa/Ptgdr2tm1Tasa
Genetic
Background		 B6.129-Ptgdr2tm1Tasa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptgdr2tm1Tasa mutation (0 available); any Ptgdr2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to type I hypersensitivity reaction ( J:197334 )
• in a model of IgE antigen-dependent passive cutaneous anaphylaxis, mice exhibit slightly increased dye extravasation (a measure of edema) compared with wild-type mice

homeostasis/metabolism
edema ( J:197334 )
• in a model of IgE antigen-dependent passive cutaneous anaphylaxis, mice exhibit slightly increased dye extravasation (a measure of edema) compared with wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory