Phenotypes Associated with This Genotype

Genotype
MGI:5517571

• Allelic Composition: Kit^W-sh/Kit^W-sh
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased susceptibility to type I hypersensitivity reaction ( J:197334 )

• following intradermally injection of BV-PLA2 or PLA2G3 into the mouse ear, mice fail to exhibit IgE and antigen induced dose-dependent vascular leakage or augmented passive cutaneous anaphylaxis unlike wild-type mice

cardiovascular system

abnormal vascular permeability ( J:197334 )

• following intradermally injection of BV-PLA2 or PLA2G3 into the mouse ear, mice fail to exhibit IgE and antigen induced dose-dependent vascular leakage or augmented passive cutaneous anaphylaxis unlike wild-type mice