Mouse Genome Informatics
hm
    Syn3tm1Jfe/Syn3tm1Jfe
B6.129X1-Syn3tm1Jfe
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in the social dominance tube test, adults show more submissive behavior than controls
• in the social transmission of food preference task, mutants show an absence of preference for the cued food over the novel food after one hour after social interaction with the demonstrator cagemate
• in the social novelty test, young mutants do not discriminate between familiar and novel mice compared to controls that spend more time exploring the novel mouse than a familiar mouse indicating altered social novelty preference
• in the resident-intruder test, mutants show reduced social interaction with the intruder mice after 1-2 months of social isolation
• however, mutants exhibit normal anxiety related behaviors

taste/olfaction
N
• olfaction is intact

Mouse Models of Human Disease
OMIM IDRef(s)
Autism 209850 J:201707