Mouse Genome Informatics
hm
    Syn1tm1Lli/Syn1tm1Lli
B6.129P2-Syn1tm1Lli
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• mutants bury fewer marbles than controls when placed in a cage with new bedding and marbles and this behavior is associated with reduced time spent in digging, whereas rearing behavior is unchanged (J:201707)
• after habituation to marbles, mutants still bury less marbles than controls, suggesting this behavior is not due to an altered response to novelty but a decrease in interest toward the environment (J:201707)
• however, mutants exhibit normal anxiety related behaviors (J:201707)
• in the social dominance tube test, adults show more dominant behavior compared to controls (J:201707)
• in the social transmission of food preference task, mutants show an absence of preference for the cued food over the novel food after one hour after social interaction with the demonstrator cagemate (J:201707)
• in the resident-intruder test, mutants show reduced social interaction with the intruder mice after 1-2 months of social isolation (J:201707)

taste/olfaction
N
• olfaction is intact (J:201707)

Mouse Models of Human Disease
OMIM IDRef(s)
Autism 209850 J:201707