Phenotypes for Dock1 Tg(MMTV-Erbb2*,-cre)1Mul MGI:5515766 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dock1^tm2.1Jfco/Dock1⁺ Tg(MMTV-Erbb2*,-cre)1Mul/0
Genetic Background	involves: C57BL/6 * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock1^tm2.1Jfco mutation (0 available); any Dock1 mutation (130 available)
Tg(MMTV-Erbb2*,-cre)1Mul mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased mammary gland tumor incidence ( J:196659 )

• with later onset than in Tg(MMTV-Erbb2*,-cre)1Mul mice

increased mammary adenocarcinoma incidence ( J:196659 )

• solid tumors

increased tumor latency ( J:196659 )

• later onset than in Tg(MMTV-Erbb2*,-cre)1Mul mice

integument

increased mammary gland tumor incidence ( J:196659 )

• with later onset than in Tg(MMTV-Erbb2*,-cre)1Mul mice

increased mammary adenocarcinoma incidence ( J:196659 )

• solid tumors

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:196659 )

• with later onset than in Tg(MMTV-Erbb2*,-cre)1Mul mice

increased mammary adenocarcinoma incidence ( J:196659 )

• solid tumors

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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