Phenotypes for Prkar2b Tg(Fabp4-cre)1Rev MGI:5515332 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Fabp4-cre)1Rev/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkar2b^tm2Gsm mutation (1 available); any Prkar2b mutation (28 available)
Prkar2b^tm3Gsm mutation (0 available); any Prkar2b mutation (28 available)
Tg(Fabp4-cre)1Rev mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased locomotor activity ( J:196157 )

• hyper-locomotor activity is retained

adipose tissue

decreased total body fat amount ( J:196157 )

decreased gonadal fat pad weight ( J:196157 )

• reproductive fat pads weigh significantly less in both males and females

growth/size/body

decreased body weight ( J:196157 )

homeostasis/metabolism

decreased circulating leptin level ( J:196157 )

• low serum leptin levels

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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