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Phenotypes Associated with This Genotype
Genotype
MGI:5512664
Allelic
Composition		 Wt1tm1.1Ceng/Wt1tm1.1Ceng
Tg(tetO-cre)LC1Bjd/0
Tg(NPHS2-rtTA2*M2)1Jbk/0
Genetic
Background		 involves: BALB/c * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(NPHS2-rtTA2*M2)1Jbk mutation (1 available)
Tg(tetO-cre)LC1Bjd mutation (2 available)
Wt1tm1.1Ceng mutation (0 available); any Wt1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
albuminuria ( J:197989 )
• progressive in doxycycline-treated mice
glomerulosclerosis ( J:197989 )
• focal segmental glomerulosclerosis in doxycycline-treated mice

homeostasis/metabolism
albuminuria ( J:197989 )
• progressive in doxycycline-treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory