Analysis Tools
limbs/digits/tail
|
• variable limb defects, with the most severe mutants having a missing autopod, fibula and distal tibia
|
|
• 26% of mice have a missing left autopod and an intact right autopod
|
|
• 63% of mice exhibit malformed autopods
|
|
• 63% of mice have substantial autopod elements on both hindlimbs, although usually with missing/malformed digits
• in forelimbs, commonly one or two anterior digits are absent
|
|
• in forelimbs, the radius is sometimes missing, but more commonly one or two anterior digits are absent
|
|
• in forelimbs, the radius is sometimes missing
|
|
• left hindlimb is usually most severely affected
|
|
• in most severely affected mutants
|
absent tibia
(
J:188812
)
|
• in most severely affected mutants
|
|
• 2 of 19 mutants have severe truncations in both hindlimbs
|
skeleton
|
• in forelimbs, the radius is sometimes missing
|
|
• in most severely affected mutants
|
absent tibia
(
J:188812
)
|
• in most severely affected mutants
|
