Phenotypes for Mapk1 Mapk3 Polr2a MGI:5508241 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Mapk1^tm1.1Hed/Mapk1^tm1.1Hed Mapk3^tm1Gpg/Mapk3^tm1Gpg Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a^{tm1(cre/ERT2)Bbd}
Genetic Background	involves: 129

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk1^tm1.1Hed mutation (0 available); any Mapk1 mutation (42 available)
Mapk3^tm1Gpg mutation (1 available); any Mapk3 mutation (25 available)
Polr2a^{tm1(cre/ERT2)Bbd} mutation (3 available); any Polr2a mutation (92 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:172200 )

• mice fed a tamoxifen-containing diet show a deterioration of health and die within 3 weeks due to multiple organ failure

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/22/2025 MGI 6.24