mortality/aging
• hemizygotes are underrepresented
• some abnormal embryos at E11.5
• apparently normal males at E13.5 but in reduced numbers
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growth/size/body
• surviving mice are smaller at birth but viable
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• surviving mice remain small throughout adulthood but are viable
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reproductive system
N |
• spermatogenesis is normal although male knockout ES cells fail to go germline
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