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Phenotypes Associated with This Genotype
Genotype
MGI:5507864
Allelic
Composition
Kdm6atm1b(EUCOMM)Jae/Y
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6atm1b(EUCOMM)Jae mutation (0 available); any Kdm6a mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• hemizygotes are underrepresented
• some abnormal embryos at E11.5
• apparently normal males at E13.5 but in reduced numbers

growth/size/body
• surviving mice are smaller at birth but viable
• surviving mice remain small throughout adulthood but are viable

reproductive system
N
• spermatogenesis is normal although male knockout ES cells fail to go germline


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory