Phenotypes Associated with This Genotype

Genotype
MGI:5503059

• Allelic Composition: Tg(KRT5-rtTA)1Glk/0; Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0; Tg(tetO/CMV-Tslp)#Sfz/0
• Genetic Background: involves: C3H * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased T cell proliferation ( J:199558 )

• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice

respiratory system inflammation ( J:199558 )

• airway inflammation in doxycycline-treated mice treated intranasally with ovalbumin

skin inflammation ( J:199558 )

• eczematous inflammation in the skin of doxycycline- and anti-mTSLP antibody-treated mice

integument

skin inflammation ( J:199558 )

• eczematous inflammation in the skin of doxycycline- and anti-mTSLP antibody-treated mice

respiratory system

respiratory system inflammation ( J:199558 )

• airway inflammation in doxycycline-treated mice treated intranasally with ovalbumin

hematopoietic system

increased T cell proliferation ( J:199558 )

• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice

cellular

increased T cell proliferation ( J:199558 )

• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice