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Phenotypes Associated with This Genotype
Genotype
MGI:5502441
Allelic
Composition		 Jam3tm1Rha/Jam3tm1Rha
Tg(Tek-Jam3)1Maal/0
Genetic
Background		 B6.Cg-Jam3tm1Rha Tg(Tek-Jam3)1Maal
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jam3tm1Rha mutation (0 available); any Jam3 mutation (24 available)
Tg(Tek-Jam3)1Maal mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:191990 )
• percentage of mutants that survive to weaning is reduced (8.2% vs. the expected 12.5%)

nervous system
hydrocephaly ( J:191990 )
• about 65% of mutants develop hydrocephalus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory