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Phenotypes Associated with This Genotype
Genotype
MGI:5502217
Allelic
Composition		 Sykm1Btlr/Sykm1Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sykm1Btlr mutation (1 available); any Syk mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased tumor necrosis factor secretion ( J:199281 )
• from macrophages stimulated with agonists LPS, MALP2 or R848

hematopoietic system

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory