Phenotypes Associated with This Genotype

Genotype
MGI:5499743

• Allelic Composition: Myh9^{tm6.1(EGFP/MYH9*)Rsad}/Myh9⁺
• Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased megakaryocyte cell number ( J:175367 )

• in the bone marrow and spleen

abnormal neutrophil morphology ( J:175367 )

• contain Myh9 aggregates

abnormal platelet morphology ( J:175367 )

• increased diameter

thrombocytopenia ( J:175367 )

• macrothrombocytopenia

homeostasis/metabolism

abnormal blood coagulation ( J:175367 )

• reduced clot retraction

increased bleeding time ( J:175367 )

immune system

abnormal neutrophil morphology ( J:175367 )

• contain Myh9 aggregates