Analysis Tools
hematopoietic system
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• mutant platelets have a membrane-related cytoskeletal defect that might account for the ex vivo adhesion defect
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• wild-type platelets adhered to collagen in small clusters, whereas adherent mutant platelets failed to aggregate with other platelets
• mutant mice formed stable thrombi less efficiently than controls; these mice usually formed thrombi as rapidly as wild-type mice, but these vascular occlusions were unstable
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homeostasis/metabolism
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• mutant platelets have a membrane-related cytoskeletal defect that might account for the ex vivo adhesion defect
|
|
• wild-type platelets adhered to collagen in small clusters, whereas adherent mutant platelets failed to aggregate with other platelets
• mutant mice formed stable thrombi less efficiently than controls; these mice usually formed thrombi as rapidly as wild-type mice, but these vascular occlusions were unstable
|
