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Phenotypes Associated with This Genotype
Genotype
MGI:5496535
Allelic
Composition
Ceacam1tm1.1Fta/Ceacam1tm1.1Fta
Genetic
Background
C57BL/6(FVB)-Ceacam1tm1.1Fta
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ceacam1tm1.1Fta mutation (0 available); any Ceacam1 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice

immune system
• infection with mouse hepatitis virus (MHV A59) infection are fully resistant to lethality and viral accumulation observed in C57BL/6 control mice
• MHV fails to replicate in peritoneal macrophages
• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory