Phenotypes for Dbh MGI:5495968 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dbh^{tm1(flpo)Pjen}/Dbh^{tm1(flpo)Pjen}
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbh^{tm1(flpo)Pjen} mutation (0 available); any Dbh mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis ( J:198264 )

• at E12.5, 4 homozygous embryos (identified from 25 total) are observed but are growth-retarded and dead or dying

prenatal lethality, complete penetrance ( J:198264 )

• no homozygous animals out of 32 pups are recovered at birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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