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Phenotypes Associated with This Genotype
Genotype
MGI:5495317
Allelic
Composition		 Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/?
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:194308 )
• embryos are viable at E14.5 but with severe limb deformities

limbs/digits/tail
abnormal limb morphology ( J:194308 )
• severe limb deformities at E14.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory