Phenotypes for Cdkn2a Hdac2 MGI:5494635 MGI Mouse

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Browsers

Phenotypes Associated with This Genotype

Allelic Composition	Cdkn2a^tm2.1Brn/Cdkn2a^tm2.1Brn Hdac2^tm1.2Rdp/Hdac2^tm1.2Rdp
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2a^tm2.1Brn mutation (0 available); any Cdkn2a mutation (59 available)
Hdac2^tm1.2Rdp mutation (1 available); any Hdac2 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal mitosis ( J:197818 )

• cell cycle arrest in mouse embryonic fibroblasts treated with Hdac1 shRNA

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/30/2025 MGI 6.24