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Phenotypes Associated with This Genotype
Genotype
MGI:5494399
Allelic
Composition		 Uso1Gt(YTA025)Byg/Uso1Gt(YTA025)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uso1Gt(YTA025)Byg mutation (0 available); any Uso1 mutation (63 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Dispersed Golgi architecture in Uso1Gt(YTA025)Byg/Uso1Gt(YTA025)Byg and Uso1Gt(AW0562)Wtsi/Uso1Gt(AW0562)Wtsi blastocysts

mortality/aging
embryonic lethality, complete penetrance ( J:195576 )
• no mice are observed at E8.5, E9.5 or E11.5
• mice die after implantation indicated by the presence of decidua lacking identifiable embryos at E8.5 and E9.5
• however, E3.5 blastocysts are recovered

cellular
abnormal Golgi apparatus morphology ( J:195576 )
• in blastocyst cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory