Phenotypes Associated with This Genotype

Genotype
MGI:5492393

• Allelic Composition: Gt(ROSA)26Sor^{tm1(Cdkn1c)Jfpa}/Gt(ROSA)26Sor⁺; Myl2^tm1(cre)Krc/Myl2⁺
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased coronary flow rate ( J:197451 )

• higher coronary flow after ischemia/reperfusion injury

abnormal heart left ventricle pressure ( J:197451 )

• significantly better cardiac function after 30 minutes of ischemia followed by 30 minutes of reperfusion than in controls

• higher left ventricle developed pressure than in controls

• higher rate pressure product

decreased myocardial infarct size ( J:197451 )

homeostasis/metabolism

decreased myocardial infarct size ( J:197451 )