Phenotypes Associated with This Genotype

Genotype
MGI:5492073

• Allelic Composition: Tg(RBP3-ELOVL4*)#Kzh/?
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal cone electrophysiology ( J:194246 )

• decline in visual performance

• photopic b wave decrease occurs only after 4 months

• photopic behavior performance at 95% of normal through 3 months

abnormal rod electrophysiology ( J:194246 )

• decline in visual performance

• decline in scotopic b wave amplitudes at all flash intensities starting at 1.4 months

• mild optokinetic tracking defects before 2.5 months with a decline of the scotopic a wave

• a further decline at 4 months linked to catastrophic loss of optomotor responsiveness