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Phenotypes Associated with This Genotype
Genotype
MGI:5491602
Allelic
Composition
Tg(Chat-COP4*H134R/EYFP,Slc18a3)6Gfng/0
Genetic
Background
B6.Cg-Tg(Chat-COP4*H134R/EYFP,Slc18a3)6Gfng/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Chat-COP4*H134R/EYFP,Slc18a3)6Gfng mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice did not improve performance in the cued version of Morris water maze
• mice do not improve time spent or distance travelled on rotarod as compared to controls
• mice visit target hole less than controls in Barnes maze test
• mice show no preference for target quadrant in Morris water maze during the probe trial, although they perform similar to controls in acquisition phase
• mice revisit arms of Y-maze more often than controls, with less spontaneous alternations
• mice consume more food and water during the dark cycle than controls
• mice consume more food and water during the dark cycle than controls

homeostasis/metabolism
• mice run almost twice as much on treadmill as controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory