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Phenotypes Associated with This Genotype
Genotype
MGI:5490539
Allelic
Composition		 Spo11tm2.1Rdco/Spo11tm2.1Rdco
Genetic
Background		 B6.129S6-Spo11tm2.1Rdco
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spo11tm2.1Rdco mutation (0 available); any Spo11 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:194067 )
• male germ cells lack double strand breaks and are defective recombination and synapsis
• however, preleptotene pairing is normal
arrest of male meiosis ( J:194067 )
• in early prophase I

cellular
abnormal male meiosis ( J:194067 )
• male germ cells lack double strand breaks and are defective recombination and synapsis
• however, preleptotene pairing is normal
arrest of male meiosis ( J:194067 )
• in early prophase I

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory