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Phenotypes Associated with This Genotype
Genotype
MGI:5488895
Allelic
Composition		 CtseC57BL/6JOlaHsd/CtseC57BL/6JOlaHsd
Genetic
Background		 involves: 129S2/SvPasHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CtseC57BL/6JOlaHsd mutation (0 available); any Ctse mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal dendritic cell antigen presentation ( J:128538 )
• Background Sensitivity: antigen processing of ovalbumin by bone marrow-derived dendritic cells is impaired in mice homozygous for cathepsin E derived from C57BL/6JOlaHsd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory