Phenotypes Associated with This Genotype

Genotype
MGI:5488895

• Allelic Composition: Ctse^{C57BL/6JOlaHsd}/Ctse^{C57BL/6JOlaHsd}
• Genetic Background: involves: 129S2/SvPasHsd * C57BL/6JOlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal immune system physiology ( J:128538 )

abnormal dendritic cell physiology ( J:128538 )

abnormal dendritic cell antigen presentation ( J:128538 )

• Background Sensitivity: antigen processing of ovalbumin by bone marrow-derived dendritic cells is impaired in mice homozygous for cathepsin E derived from C57BL/6JOlaHsd