Analysis Tools
homeostasis/metabolism
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• at room temperature and during acute cold exposure
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• in mice fed standard chow but not a high fat diet
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• in mice fed standard chow or a high fat diet
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adipose tissue
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• in mice fed standard chow
• however, fat mass is normal in mice fed a high fat diet
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• impaired nonshivering thermogenesis above brown adipose tissue treated with the selective beta-3 adrenergic receptor agonist CL-316,243
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cellular
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• fewer and shorter cristae displaced to the periphery with varying degrees of disorientation in the mitochondria of brown adipose tissue
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• in the mitochondria of brown adipose tissue
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• decreased oxidative capacity in the mitochondria of brown adipose tissue
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growth/size/body
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• in mice fed a high fat diet
• however, lean mass is normal in mice fed standard chow
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• in mice fed standard chow or a high fat diet
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liver/biliary system
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• in mice fed standard chow or a high fat diet
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behavior/neurological
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• mice fed standard chow or a high fat diet exhibit normal food intake
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• reduced locomotor activity (total and mean dark but not mean light)
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